Top 10 Best Dog Flea and Tick Treatments

Sale# 1
K9 Advantix II Flea and Tick Prevention for Extra-Large Dogs 1-Pack 4 Monthly Doses, Over 55 Pounds
24,126 Reviews
K9 Advantix II Flea and Tick Prevention for Extra-Large Dogs 1-Pack 4 Monthly Doses, Over 55 Pounds
  • 4 monthly applications of K9 Advantix II flea and tick prevention for extra-large dogs weighing 55 pounds or more
  • K9 Advantix II flea and tick prevention for dogs works through contact, so fleas, ticks and mosquitoes do not have to bite your dog to die
  • K9 Advantix II flea and tick control for dogs is an easy to apply topical formula
  • Starts working to kill fleas within 12 hours and keeps working for 30 days
  • Suitable for effective year-round dog flea and tick treatment for extra-large dogs
Sale# 2
PETARMOR Plus for Dogs Flea and Tick Prevention for Dogs, Long-Lasting & Fast-Acting Topical Dog Flea Treatment, 3 Count, PetArmor Plus Flea & Tick Prevention for Large Dogs with Fipronil (45 to 88 Pounds), 3 Monthly Treatments
8,916 Reviews
PETARMOR Plus for Dogs Flea and Tick Prevention for Dogs, Long-Lasting & Fast-Acting Topical Dog Flea Treatment, 3 Count, PetArmor Plus Flea & Tick Prevention for Large Dogs with Fipronil (45 to 88 Pounds), 3 Monthly Treatments
  • EFFECTIVE, WATERPROOF FLEA TREATMENT FOR DOGS: PetArmor Plus is a waterproof, flea & tick topical prevention for dogs that kills fleas, flea eggs, flea larvae, ticks, and chewing lice for up to 30 days after application.
  • TRUSTED, VET QUALITY FORMULA: Containing fipronil and (S)-methoprene, the same active ingredients as FRONTLINE Plus for Dogs. PetArmor Plus for Dogs has a powerful formula that starts to kill fleas within 24 hours.
  • BREAK THE FLEA CYCLE: Unlike other flea and tick treatments that may temporarily suppress flea activity, PETARMOR Plus Dog Flea Treatment works by effectively breaking the flea life cycle. Kill flea eggs and larvae to prevent re-infestation.
  • FAST ACTNG LONG-LASTING FLEA AND TICK PROTECTION: One application of PetArmor Plus lasts up to 30 days nose to tail. A 6-dose package lasts up to six months.
  • EASY-TO-USE, LONG-LASTING: PetArmor Plus flea and tick treatment comes with three (3) waterproof topical applications that provides your pet flea protection and control for three (3) months.
Sale# 3
K9 Advantix II Flea and Tick Prevention for Large Dogs 4-Pack, 21-55 Pounds
21,684 Reviews
K9 Advantix II Flea and Tick Prevention for Large Dogs 4-Pack, 21-55 Pounds
  • 4 monthly applications of K9 Advantix II flea and tick prevention for large dogs weighing 21-55 pounds
  • K9 Advantix II flea and tick prevention for dogs works through contact, so fleas, ticks and mosquitoes do not have to bite your dog to die
  • K9 Advantix II flea and tick control for dogs is an easy to apply topical formula
  • Starts working to kill fleas within 12 hours and keeps working for 30 days
  • Suitable for effective year-round dog flea and tick treatment for large dogs
# 4
Vet's Best Flea and Tick Home Spray | Flea Treatment for Dogs and Home | Flea Killer with Certified Natural Oils | 32 Ounces
34,951 Reviews
Vet's Best Flea and Tick Home Spray | Flea Treatment for Dogs and Home | Flea Killer with Certified Natural Oils | 32 Ounces
  • NO HARSH CHEMICALS: Vet’s Best Flea and Tick Home Spray kills fleas, flea larvae, flea eggs, ticks and mosquitoes by contact without harsh chemicals
  • PROVEN EFFECTIVE: Whether facing an active infestation or are applying for routine prevention, our spray is scientifically proven effective against pests but gentle enough to use around the whole family
  • CERTIFIED NATURAL OILS: Each steam-distilled essential oil is selected for its potent pest-fighting properties and is 100% Certified Natural
  • TOTAL HOME DEFENSE: Applies easily on surfaces, indoors and out, including dog bedding, crates, furniture, blankets, upholstery, carpets, outdoor surfaces, and more. Also gentle enough to be applied directly on dogs and puppies 12 weeks or older
# 5
Frontline Plus Flea and Tick Treatment for Dogs (Large Dog, 45-88 Pounds, 3 Doses)
12,243 Reviews
Frontline Plus Flea and Tick Treatment for Dogs (Large Dog, 45-88 Pounds, 3 Doses)
  • Waterproof flea and tick treatment for dogs: Frontline Plus for Dogs provides waterproof, fast-acting, long-lasting flea and tick treatment and control for your dog. This product is approved for use on dogs 45-88 lbs.
  • Break the flea life cycle with frontline: Frontline flea and tick treatment for dogs kills adult fleas plus flea eggs and larvae to stop existing infestations and prevent establishment of new infestations.
  • Kills fleas and ticks: Frontline flea and tick treatment for dogs kills fleas, flea eggs, lice, and ticks. This flea and tick treatment kills ticks, including those that may transmit Lyme disease.
  • Trusted flea and tick protection for dogs: Frontline has been trusted by veterinarians for nearly 20 years. Made with 2 tough killing ingredients, fipronil and (S)-methoprene – one to kill adult fleas and ticks and the second to kill flea eggs and larvae – this fast-acting, long-lasting protection provides flea and tick control for dogs and puppies 8 weeks and older
  • Lasting flea and tick protection: Frontline's long-lasting formula is stored in the oil glands of the pet’s skin to give non-stop flea and tick protection for a full 30 days. Frontline flea and tick treatment for dogs works non-stop for a full 30 days. A 3-dose supply lasts for 3 months.
Sale# 6
Amazon Brand - Solimo Flea and Tick Topical Treatment for Dogs, For Small Dogs (5-22 pounds), 3 Doses
11,422 Reviews
Amazon Brand - Solimo Flea and Tick Topical Treatment for Dogs, For Small Dogs (5-22 pounds), 3 Doses
  • Includes three 0.023 fluid ounce tubes of Solimo Topical Flea and Tick Treatment for Small Dogs (5 - 22 pounds)
  • Solimo topical flea and tick prevention for dogs kills fleas, flea eggs, flea larvae, ticks, and chewing lice for up to 30 days after application
  • Contains fipronil, and (s)-methoprene, the same active ingredients used in Frontline Plus
  • For best results, apply directly to dry skin on your dog's back-between the shoulder blades-on a monthly basis and treat your home and yard at the same time
  • A fast-acting, long lasting topical flea treatment for dogs that stops the flea life cycle and kills flea eggs and larvae for up to 4 weeks
  • Kills deer ticks that may transmit Lyme disease
  • Waterproof topical applications
  • If any side effects occur or your dog has unusual reaction to the application, consult your veterinarian or call 1-877-416-7330; For questions and comments about the product or product usage, please call 1-888-814-4738 (4PET)
  • Satisfaction Guarantee: We're proud of our products. If you aren't satisfied, we'll refund you for any reason within a year of purchase. 1-877-485-0385
  • An Amazon brand
# 7
PetArmor for Dogs, Flea and Tick Treatment for Large Dogs (45-88 Pounds), Includes 3 Month Supply of Topical Flea Treatments
1,119 Reviews
PetArmor for Dogs, Flea and Tick Treatment for Large Dogs (45-88 Pounds), Includes 3 Month Supply of Topical Flea Treatments
  • DOG FLEA AND TICK CONTROL: PetArmor topical flea and tick treatment kills adult fleas, ticks and chewing lice. Backed by the PetArmor Protection Guarantee.
  • VET QUALITY FORMULA: Dog flea treatment contains the active ingredient fipronil.
  • FAST-ACTING FLEA TREATMENT: PetArmor flea treatment for dogs can help you stop an existing flea or tick infestation.
  • FLEA AND TICK PREVENTION: PetArmor for dogs helps you protect your furry family member from brown dog ticks, American dog ticks, lone star ticks, and deer ticks (which may transmit Lyme disease).
  • INCLUDES: Three (3) topical application tubes for a 3 month supply of dog and flea and tick control. For best results, apply flea & tick treatment for dogs directly to dry skin on your dog's back-between the shoulder blades-on a monthly basis.
# 8
PETARMOR Plus for Dogs Flea and Tick Prevention for Dogs, Long-Lasting & Fast-Acting Topical Dog Flea Treatment, 6 Count
8,245 Reviews
PETARMOR Plus for Dogs Flea and Tick Prevention for Dogs, Long-Lasting & Fast-Acting Topical Dog Flea Treatment, 6 Count
  • EFFECTIVE, WATERPROOF FLEA TREATMENT FOR DOGS: PetArmor Plus is a waterproof, flea & tick topical prevention for dogs that kills fleas, flea eggs, flea larvae, ticks, and chewing lice for up to 30 days after application.
  • TRUSTED, VET QUALITY FORMULA: Containing fipronil and (S)-methoprene, the same active ingredients as FRONTLINE Plus for Dogs. PetArmor Plus for Dogs has a powerful formula that starts to kill fleas within 24 hours.
  • BREAK THE FLEA CYCLE: Unlike other flea and tick treatments that may temporarily suppress flea activity, PETARMOR Plus Dog Flea Treatment works by effectively breaking the flea life cycle. Kill flea eggs and larvae to prevent re-infestation.
  • FAST ACTNG LONG-LASTING FLEA AND TICK PROTECTION: One application of PetArmor Plus lasts up to 30 days nose to tail. A 6-dose package lasts up to six months.
  • EASY-TO-USE, LONG-LASTING: PetArmor Plus flea and tick treatment comes with six (6) waterproof topical applications that provide your pet flea protection and control for (6) months.
Sale# 9
SENTRY Fiproguard for Dogs, Flea and Tick Prevention for Dogs (45-88 Pounds), Includes 6 Month Supply of Topical Flea Treatments
1,060 Reviews
SENTRY Fiproguard for Dogs, Flea and Tick Prevention for Dogs (45-88 Pounds), Includes 6 Month Supply of Topical Flea Treatments
  • DOG FLEA AND TICK CONTROL: SENTRY Fiproguard topical flea and tick prevention for dogs kills fleas, ticks and chewing lice for up to 30 days.
  • VET QUALITY FORMULA: SENTRY Fiproguard is a vet-quality formula flea treatment that contains fipronil.
  • LARGE DOGS: Flea and tick control for use on dogs and puppies over 8 weeks of age, weighing 45-88 pounds; can be used on breeding, pregnant, and lactating dogs.
  • TICK PREVENTION: Fiproguard for dogs also kills brown dog ticks, American dog ticks, lone star ticks and deer ticks (which may transmit Lyme disease).
  • INCLUDES: Six (6) 0.091 fl. oz. applicators, a six month supply of waterproof topical applications for dog flea and tick control. For best results, apply flea & tick treatment for dogs directly to dry skin on your dog's back-between the shoulder blades-on a monthly basis.
# 10
Vet’s Best Flea and Tick Advanced Strength Dog Shampoo | Flea Treatment for Dogs | Flea Killer with Certified Natural Oils | 12 Ounces
4,210 Reviews
Vet’s Best Flea and Tick Advanced Strength Dog Shampoo | Flea Treatment for Dogs | Flea Killer with Certified Natural Oils | 12 Ounces
  • 2X FLEA KILLING EFFECTIVENESS not only kills fleas, flea larva, flea eggs, and ticks on contact but cleans and deodorizes your dog’s coat
  • VET'S BEST FLEA & TICK ADVANCED STRENGTH SHAMPOO does not contain harsh chemicals, but rather 100% certified natural essential oils and plant-based ingredients that provide a safe and fast acting formula for flea and tick removal and prevention
  • NO ADDED FRAGRANCE – Made with 100% certified natural essential oils the Vet’s Best Flea & Tick Shampoo has a rosemary and peppermint scent that is easy to lather & rinse.
  • SAFE TO USE for dogs and puppies 12 weeks or older when used as directed. Can be applied indoors or outdoors.

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