Top 10 Best Dog Flea and Tick Treatments

# 1
Frontline Plus Flea and Tick Treatment for Dogs (Large Dog, 45-88 Pounds, 3 Doses)
11,192 Reviews
Frontline Plus Flea and Tick Treatment for Dogs (Large Dog, 45-88 Pounds, 3 Doses)
  • Waterproof flea and tick treatment for dogs: Frontline Plus for Dogs provides waterproof, fast-acting, long-lasting flea and tick treatment and control for your dog. This product is approved for use on dogs 45-88 lbs.
  • Break the flea life cycle with frontline: Frontline flea and tick treatment for dogs kills adult fleas plus flea eggs and larvae to stop existing infestations and prevent establishment of new infestations.
  • Kills fleas and ticks: Frontline flea and tick treatment for dogs kills fleas, flea eggs, lice, and ticks. This flea and tick treatment kills ticks, including those that may transmit Lyme disease.
  • Trusted flea and tick protection for dogs: Frontline has been trusted by veterinarians for nearly 20 years. Made with 2 tough killing ingredients, fipronil and (S)-methoprene – one to kill adult fleas and ticks and the second to kill flea eggs and larvae – this fast-acting, long-lasting protection provides flea and tick control for dogs and puppies 8 weeks and older
  • Lasting flea and tick protection: Frontline's long-lasting formula is stored in the oil glands of the pet’s skin to give non-stop flea and tick protection for a full 30 days. Frontline flea and tick treatment for dogs works non-stop for a full 30 days. A 3-dose supply lasts for 3 months.
# 2
Frontline Plus Flea and Tick Treatment for Dogs (Small Dog, 5-22 Pounds, 3 Doses)
13,993 Reviews
Frontline Plus Flea and Tick Treatment for Dogs (Small Dog, 5-22 Pounds, 3 Doses)
  • Waterproof flea and tick treatment for dogs: Frontline Plus for Dogs provides waterproof, fast-acting, long-lasting flea and tick treatment and control for your dog. This product is approved for use on dogs 5-22 lbs.
  • Break the flea life cycle with frontline: Frontline flea and tick treatment for dogs kills adult fleas plus flea eggs and larvae to stop existing infestations and prevent establishment of new infestations.
  • Kills fleas and ticks: Frontline flea and tick treatment for dogs kills fleas, flea eggs, lice, and ticks. This flea and tick treatment kills ticks, including those that may transmit Lyme disease.
  • Trusted flea and tick protection for dogs: Frontline has been trusted by veterinarians for nearly 20 years. Made with 2 tough killing ingredients, fipronil and (S)-methoprene – one to kill adult fleas and ticks and the second to kill flea eggs and larvae – this fast-acting, long-lasting protection provides flea and tick control for dogs and puppies 8 weeks and older
  • Lasting flea and tick protection: Frontline's long-lasting formula isstored in the oil glands of the pet’s skin to give non-stop flea and tick protection for a full 30 days. Frontline flea and tick treatment for dogs works non-stop for a full 30 days. A 3-dose supply lasts for 3 months.
# 3
Seresto Flea and Tick Collar for Dogs, 8-Month Flea and Tick Collar for Large Dogs Over 18 Pounds
42,242 Reviews
Seresto Flea and Tick Collar for Dogs, 8-Month Flea and Tick Collar for Large Dogs Over 18 Pounds
  • Provides 8-months of continuous flea and tick prevention
  • Seresto flea and tick collar for large dogs works through contact, so fleas and ticks do not have to bite your dog to die
  • Veterinarian-recommended flea and tick prevention for dogs in a convenient, odorless and non-greasy collar; No need for messy monthly treatments
  • Starts to repel and kill fleas within 24 hours of initial application
  • Flea and tick collar for large dogs also helps treat and control sarcoptic mange and kills lice
# 4
K9 Advantix II Flea and Tick Prevention for Large Dogs 2-Pack, 21-55 Pounds
20,184 Reviews
K9 Advantix II Flea and Tick Prevention for Large Dogs 2-Pack, 21-55 Pounds
  • 2 monthly applications of K9 Advantix II flea and tick prevention for large dogs weighing 21-55 pounds
  • K9 Advantix II flea and tick prevention for dogs works through contact, so fleas, ticks and mosquitoes do not have to bite your dog to die
  • K9 Advantix II flea and tick control for dogs is an easy to apply topical formula
  • Starts working to kill fleas within 12 hours and keeps working for 30 days
  • Suitable for effective year-round dog flea and tick treatment for large dogs
# 5
Capstar Fast-Acting Oral Flea Treatment for Large Dogs, 6 Doses, 57 mg (26-125 lbs)
10,750 Reviews
Capstar Fast-Acting Oral Flea Treatment for Large Dogs, 6 Doses, 57 mg (26-125 lbs)
  • FAST-ACTING FLEA TREATMENT: One oral flea tablet starts killing fleas within 30 minutes.
  • TACKLE FLEA INFESTATIONS FAST: Give Capstar oral flea treatment and watch dead fleas fall off your pet.
  • TREAT RE-INFESTATIONS FAST: If your pet gets re-invested with fleas, simply give another dose as often as once a day.
  • WITHOUT A VET PRESCRIPTION: Flea treatment without needing a veterinarian prescription, administer this cat flea tablet orally to kill adult fleas fast.
  • KILL ADULT FLEAS: Capstar oral flea treatment tablets (57 mg) are safe for dogs and puppies from 25.1-125 lbs., four (4) weeks and older.
Sale# 6
K9 Advantix II Flea and Tick Prevention for Extra-Large Dogs 1-Pack 4 Monthly Doses, Over 55 Pounds
6,526 Reviews
K9 Advantix II Flea and Tick Prevention for Extra-Large Dogs 1-Pack 4 Monthly Doses, Over 55 Pounds
  • 4 monthly applications of K9 Advantix II flea and tick prevention for extra-large dogs weighing 55 pounds or more
  • K9 Advantix II flea and tick prevention for dogs works through contact, so fleas, ticks and mosquitoes do not have to bite your dog to die
  • K9 Advantix II flea and tick control for dogs is an easy to apply topical formula
  • Starts working to kill fleas within 12 hours and keeps working for 30 days
  • Suitable for effective year-round dog flea and tick treatment for extra-large dogs
# 7
Vet's Best Flea and Tick Home Spray | Flea Treatment for Dogs and Home | Flea Killer with Certified Natural Oils | 32 Ounces
37,298 Reviews
Vet's Best Flea and Tick Home Spray | Flea Treatment for Dogs and Home | Flea Killer with Certified Natural Oils | 32 Ounces
  • NO HARSH CHEMICALS: Vet’s Best Flea and Tick Home Spray kills fleas, flea larvae, flea eggs, ticks and mosquitoes by contact without harsh chemicals
  • PROVEN EFFECTIVE: Whether facing an active infestation or are applying for routine prevention, our spray is scientifically proven effective against pests but gentle enough to use around the whole family
  • CERTIFIED NATURAL OILS: Each steam-distilled essential oil is selected for its potent pest-fighting properties and is 100% Certified Natural
  • TOTAL HOME DEFENSE: Applies easily on surfaces, indoors and out, including dog bedding, crates, furniture, blankets, upholstery, carpets, outdoor surfaces, and more. Also gentle enough to be applied directly on dogs and puppies 12 weeks or older
Sale# 8
PETARMOR Plus for Dogs Flea and Tick Prevention for Dogs, Long-Lasting & Fast-Acting Topical Dog Flea Treatment, 3 Count, PetArmor Plus Flea & Tick Prevention for Large Dogs with Fipronil (45 to 88 Pounds), 3 Monthly Treatments
8,138 Reviews
PETARMOR Plus for Dogs Flea and Tick Prevention for Dogs, Long-Lasting & Fast-Acting Topical Dog Flea Treatment, 3 Count, PetArmor Plus Flea & Tick Prevention for Large Dogs with Fipronil (45 to 88 Pounds), 3 Monthly Treatments
  • EFFECTIVE, WATERPROOF FLEA TREATMENT FOR DOGS: PetArmor Plus is a waterproof, flea & tick topical prevention for dogs that kills fleas, flea eggs, flea larvae, ticks, and chewing lice for up to 30 days after application.
  • TRUSTED, VET QUALITY* FORMULA: Containing fipronil and (S)-methoprene, the same active ingredients as FRONTLINE Plus for Dogs. PetArmor Plus for Dogs has a powerful formula that starts to kill fleas within 24 hours.
  • BREAK THE FLEA CYCLE: Unlike other flea and tick treatments that may temporarily suppress flea activity, PETARMOR Plus Dog Flea Treatment works by effectively breaking the flea life cycle! Kill flea eggs and larvae to prevent re-infestation.
  • FAST ACTNG LONG-LASTING FLEA AND TICK PROTECTION: One application of PetArmor Plus lasts up to 30 days nose to tail. A 6-dose package lasts up to six months.
  • EASY-TO-USE, LONG-LASTING: PetArmor Plus flea and tick treatment comes with three (3) waterproof topical applications that provides your pet flea protection and control for three (3) months.
Sale# 9
TevraPet Activate II Flea and Tick Prevention for Dogs - 4 Months Topical Flea and Tick Treatment and Control, 55+ lbs
2,566 Reviews
TevraPet Activate II Flea and Tick Prevention for Dogs - 4 Months Topical Flea and Tick Treatment and Control, 55+ lbs
  • Vet quality - Contains imidacloprid, permethrin and pyriproxyfen, the active ingredients found in K9 Advantix II for Dogs
  • Repels - proven to Repel fleas, flea eggs, ticks, biting flies and mosquitoes. Does not require biting!
  • Effective - This broad spectrum flea and tick topical kills all stages of fleas, flea eggs, ticks, and lice
  • Easy-to-apply - four month supply, use monthly on your dog. No need to reapply after swimming or bathing. Available in four convenient weight breaks. No biting required to kill the pest.
  • American made - proudly made in the USA
# 10
PetArmor Plus for Dogs Flea and Tick Prevention for Dogs, Long-Lasting & Fast-Acting Topical Dog Flea Treatment, 6 Count, small
6,515 Reviews
PetArmor Plus for Dogs Flea and Tick Prevention for Dogs, Long-Lasting & Fast-Acting Topical Dog Flea Treatment, 6 Count, small
  • EFFECTIVE, WATERPROOF FLEA TREATMENT FOR DOGS: PetArmor Plus is a waterproof, flea & tick topical prevention for dogs that kills fleas, flea eggs, flea larvae, ticks, and chewing lice for up to 30 days after application.
  • TRUSTED, VET QUALITY* FORMULA: Containing fipronil and (S)-methoprene, the same active ingredients as FRONTLINE Plus for Dogs. PetArmor Plus for Dogs has a powerful formula that starts to kill fleas within 24 hours.
  • BREAK THE FLEA CYCLE: Unlike other flea and tick treatments that may temporarily suppress flea activity, PETARMOR Plus Dog Flea Treatment works by effectively breaking the flea life cycle! Kill flea eggs and larvae to prevent re-infestation.
  • FLEA AND TICK PROTECTION: PetArmor Plus for Dogs flea drops protects your furry family members from brown dog ticks, American dog ticks, Lone Star ticks, and deer ticks (which may transmit Lyme disease).
  • EASY-TO-USE, LONG-LASTING: PetArmor Plus flea and tick treatment comes with six (6) waterproof topical applications that provide your pet flea protection and control for six (6) months.

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