Top 10 Best Dog Flea and Tick Treatments

# 1
FRONTLINE Plus Flea and Tick Treatment for Dogs (Large Dog, 45-88 Pounds, 3 Doses)
8,912 Reviews
FRONTLINE Plus Flea and Tick Treatment for Dogs (Large Dog, 45-88 Pounds, 3 Doses)
  • Waterproof flea and tick treatment for dogs: Frontline Plus for Dogs provides waterproof, fast-acting, long-lasting flea and tick treatment and control for your dog. This product is approved for use on dogs 45-88 lbs.
  • Break the flea life cycle with frontline: Frontline flea and tick treatment for dogs kills adult fleas plus flea eggs and larvae to stop existing infestations and prevent establishment of new infestations.
  • Kills fleas and ticks: Frontline flea and tick treatment for dogs kills fleas, flea eggs, lice, and ticks. This flea and tick treatment kills ticks, including those that may transmit Lyme disease.
  • Trusted flea and tick protection for dogs: Frontline has been trusted by veterinarians for nearly 20 years. Made with 2 tough killing ingredients, fipronil and (S)-methoprene – one to kill adult fleas and ticks and the second to kill flea eggs and larvae – this fast-acting, long-lasting protection provides flea and tick control for dogs and puppies 8 weeks and older
  • Lasting flea and tick protection: Frontline's long-lasting formula isstored in the oil glands of the pet’s skin to give non-stop flea and tick protection for a full 30 days. Frontline flea and tick treatment for dogs works non-stop for a full 30 days. A 3-dose supply lasts for 3 months.
  • If you are not satisfied with Frontline Plus for any reason, please contact the Boehringer-Ingelheim Animal Health Customer Care Team at: 1-800-660-1842.
# 2
K9 Advantix II Flea and Tick Prevention for Large Dogs 2-Pack, 21-55 Pounds
5,593 Reviews
K9 Advantix II Flea and Tick Prevention for Large Dogs 2-Pack, 21-55 Pounds
  • 2 monthly applications of K9 Advantix II flea and tick prevention for large dogs weighing 21-55 pounds
  • K9 Advantix II flea and tick prevention for dogs works through contact, so fleas, ticks and mosquitoes do not have to bite your dog to die
  • K9 Advantix II flea and tick control for dogs is an easy to apply topical formula
  • Starts working to kill fleas within 12 hours and keeps working for 30 days
  • Suitable for effective year-round dog flea and tick treatment for large dogs
Sale# 3
K9 Advantix II Flea and Tick Prevention for Extra-Large Dogs 4-Pack, Over 55 Pounds
4,632 Reviews
K9 Advantix II Flea and Tick Prevention for Extra-Large Dogs 4-Pack, Over 55 Pounds
  • 4 monthly applications of K9 Advantix II flea and tick prevention for extra-large dogs weighing 55 pounds or more
  • K9 Advantix II flea and tick prevention for dogs works through contact, so fleas, ticks and mosquitoes do not have to bite your dog to die
  • K9 Advantix II flea and tick control for dogs is an easy to apply topical formula
  • Starts working to kill fleas within 12 hours and keeps working for 30 days
  • Suitable for effective year-round dog flea and tick treatment for extra-large dogs
# 4
Vet's Best Flea and Tick Home Spray | Flea Treatment for Dogs and Home | Flea Killer with Certified Natural Oils | 32 Ounces
28,607 Reviews
Vet's Best Flea and Tick Home Spray | Flea Treatment for Dogs and Home | Flea Killer with Certified Natural Oils | 32 Ounces
  • NO HARSH CHEMICALS - Vet’s Best Flea and Tick Home Spray kills fleas, flea larvae, flea eggs, ticks and mosquitoes by contact without harsh chemicals. Proven Effective - Whether facing an active infestation or are applying for routine prevention, our spray is scientifically proven effective against pests but gentle enough to use around the whole family. Certified Natural Oils - Each steam-distilled essential oil is selected for its potent pest-fighting properties and is 100% Certified Natural. Total Home Defense- Applies easily on surfaces, indoors and out, including dog bedding, crates, furniture, blankets, upholstery, carpets, outdoor surfaces, and more. Also gentle enough to be applied directly on dogs and puppies 12 weeks or older. USA Made - Each 32 oz bottle is Made in the USA and can be refilled with the Vet's Best Home Spray 96 oz Refill.
# 5
K9 Advantix II Flea and Tick Prevention for Medium Dogs, 11-20 Pounds
10,036 Reviews
K9 Advantix II Flea and Tick Prevention for Medium Dogs, 11-20 Pounds
  • K9 Advantix II for dogs works through contact, so fleas, ticks and mosquitoes don’t have to bite your dog to die
  • K9 Advantix II topical tick and flea control for dogs is easy to apply, starts working to kill fleas within 12 hours and keeps working for 30 days
  • Veterinarian recommended Bayer K9 Advantix II for dogs also repels biting flies and kills lice
  • Contains 1 monthly application of K9 Advantix II dog flea and tick treatment
# 6
FRONTLINE Plus Flea and Tick Treatment for Dogs (Small Dog, 5-22 Pounds, 3 Doses)
11,399 Reviews
FRONTLINE Plus Flea and Tick Treatment for Dogs (Small Dog, 5-22 Pounds, 3 Doses)
  • Waterproof flea and tick treatment for dogs: Frontline Plus for Dogs provides waterproof, fast-acting, long-lasting flea and tick treatment and control for your dog. This product is approved for use on dogs 5-22 lbs.
  • Break the flea life cycle with frontline: Frontline flea and tick treatment for dogs kills adult fleas plus flea eggs and larvae to stop existing infestations and prevent establishment of new infestations.
  • Kills fleas and ticks: Frontline flea and tick treatment for dogs kills fleas, flea eggs, lice, and ticks. This flea and tick treatment kills ticks, including those that may transmit Lyme disease.
  • Trusted flea and tick protection for dogs: Frontline has been trusted by veterinarians for nearly 20 years. Made with 2 tough killing ingredients, fipronil and (S)-methoprene – one to kill adult fleas and ticks and the second to kill flea eggs and larvae – this fast-acting, long-lasting protection provides flea and tick control for dogs and puppies 8 weeks and older
  • Lasting flea and tick protection: Frontline's long-lasting formula isstored in the oil glands of the pet’s skin to give non-stop flea and tick protection for a full 30 days. Frontline flea and tick treatment for dogs works non-stop for a full 30 days. A 3-dose supply lasts for 3 months.
  • Customer care: If you are not satisfied with Frontline Plus for any reason, please contact the Boehringer-Ingelheim Animal Health Customer care Team at: 1-800-660-1842.
  • If you are not satisfied with Frontline Plus for any reason, please contact the Boehringer-Ingelheim Animal Health Customer Care Team at: 1-800-660-1842.
# 7
Capstar Fast-Acting Oral Flea Treatment for Large Dogs, 6 Doses, 57 mg (26-125 lbs)
7,829 Reviews
Capstar Fast-Acting Oral Flea Treatment for Large Dogs, 6 Doses, 57 mg (26-125 lbs)
  • Includes 6 doses for use with dogs weighing 25. 1 – 125 (57 mg) pounds
  • One oral tablet starts killing fleas within 30 minutes of administration
  • Tackle flea infestations fast – give Capstar and watch dead fleas fall off your pet
  • The convenience of an oral tablet available without a prescription from your vet
  • If your pet gets re-infested with fleas, you can safely give another dose as often as once per day
Sale# 8
PETARMOR Plus for Dogs Flea and Tick Prevention for Dogs, Long-Lasting & Fast-Acting Topical Dog Flea Treatment, 3 Count, PetArmor Plus Flea & Tick Prevention for Large Dogs with Fipronil (45 to 88 Pounds), 3 Monthly Treatments
5,559 Reviews
PETARMOR Plus for Dogs Flea and Tick Prevention for Dogs, Long-Lasting & Fast-Acting Topical Dog Flea Treatment, 3 Count, PetArmor Plus Flea & Tick Prevention for Large Dogs with Fipronil (45 to 88 Pounds), 3 Monthly Treatments
  • EFFECTIVE, WATERPROOF FLEA TREATMENT FOR DOGS: PetArmor Plus is a fully waterproof, flea & tick topical prevention for cats that kills fleas, flea eggs, flea larvae, ticks, and chewing lice for up to 30 days after application.
  • TRUSTED, VET QUALITY* FORMULA: Containing fipronil and the same active ingredients as Frontline Plus for Dogs, PetArmor Plus for Dogs has been trusted by vetinarians for nearly 20 years due to a powerful formula that kills fleas within 24 hours.
  • BREAK THE FLEA CYCLE: Unlike other flea and tick treatments that may just temporarily suppress flea activity, PETARMOR Plus Dog Flea Treatment works by breaking the flea cycle entirely! Kill flea eggs and larvae for up to 12 weeks
  • ULTIMATE FLEA AND TICK PROTECTION: PetArmor Plus for Dogs protects your furry family member from brown dog Ticks, American dog ticks, Lone Star ticks, and deer ticks (which may transmit Lyme disease)
  • LONG-LASTING: This flea and tick treatment comes with three (3) 0.017 fl. Oz. Waterproof topical applications that are good for three months of flea protection for your pet.
# 9
Seresto Flea and Tick Collar for Dogs, 8-Month Flea and Tick Collar for Large Dogs Over 18 Pounds
35,593 Reviews
Seresto Flea and Tick Collar for Dogs, 8-Month Flea and Tick Collar for Large Dogs Over 18 Pounds
  • Provides 8-months of continuous flea and tick prevention
  • Seresto flea and tick collar for large dogs works through contact, so fleas and ticks do not have to bite your dog to die
  • Veterinarian-recommended flea and tick prevention for dogs in a convenient, odorless and non-greasy collar; No need for messy monthly treatments
  • Starts to repel and kill fleas within 24 hours of initial application
  • Flea and tick collar for large dogs also helps treat and control sarcoptic mange and kills lice
# 10
PETARMOR Plus for Dogs Flea and Tick Prevention for Dogs, Long-Lasting & Fast-Acting Topical Dog Flea Treatment, 6 Count
5,338 Reviews
PETARMOR Plus for Dogs Flea and Tick Prevention for Dogs, Long-Lasting & Fast-Acting Topical Dog Flea Treatment, 6 Count
  • EFFECTIVE, WATERPROOF FLEA TREATMENT FOR DOGS: PetArmor Plus is a fully waterproof, flea & tick topical prevention for cats that kills fleas, flea eggs, flea larvae, ticks, and chewing lice for up to 30 days after application.
  • TRUSTED, VET QUALITY* FORMULA: Containing fipronil and the same active ingredients as Frontline Plus for Dogs, PetArmor Plus for Dogs has been trusted by vetinarians for nearly 20 years due to a powerful formula that kills fleas within 24 hours.
  • BREAK THE FLEA CYCLE: Unlike other flea and tick treatments that may just temporarily suppress flea activity, PETARMOR Plus Dog Flea Treatment works by breaking the flea cycle entirely! Kill flea eggs and larvae for up to 12 weeks
  • ULTIMATE FLEA AND TICK PROTECTION: PetArmor Plus for Dogs protects your furry family member from brown dog Ticks, American dog ticks, Lone Star ticks, and deer ticks (which may transmit Lyme disease)
  • LONG-LASTING: This flea and tick treatment comes with six (3) 0.017 fl. Oz. Waterproof topical applications that are good for six months of flea protection for your pet.

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